Dual inhibition of human type 4 phosphodiesterase isostates by (R*,R*)-(-+)-methyl 3-acety-4...
- Resource Type
- Article
- Authors
- Tian, Gaochao; Rocque, Warren J.; Wiseman, Jeffrey S.; Thompson, Irene Z.; Holmes, William D.; Domanico, Paul L.; Stafford, Jeffrey A.; Feldman, Paul L.; Luther, Michael A.
- Source
- Biochemistry. 05/12/98, Vol. 37 Issue 19, p6894. 11p. 3 Diagrams, 3 Charts, 15 Graphs.
- Subject
- *BIOCHEMISTRY
*PHOSPHODIESTERASES
- Language
- ISSN
- 0006-2960
Presents information pertaining to the existence of human type 4 phosphodiesterase B2B (HSPDE4B2B) which has the characteristics of being purified and recombinant. How does the HSPDE4B2B exists; Circumstances surrounding the significant difference of the tissue distribution of the two isostates; Demonstration of binding experiments.