Amphiphiles, Gaucher Disease, Carbohydrates, Pharmacological chaperones, Self-assembly The noodles in the soup represent the misfolded GCase enzyme, which is stabilized by our compound as a monomer in the nM concentration range and symbolized by the spoon. Keywords: Amphiphiles; Gaucher Disease; Carbohydrates; Pharmacological chaperones; Self-assembly EN Amphiphiles Gaucher Disease Carbohydrates Pharmacological chaperones Self-assembly 1 1 1 03/16/23 20230314 NES 230314 B The Front Cover b shows a picture of a Ramen bowl, the famous Japanese noodle soup, that allegorically sketches the combination of the different aggregation states of the amphiphilic GCase pharmacological chaperone, object of our study. [Extracted from the article]