Successful anesthetic management of patients with adrenal tumors requires a well-orchestrated and multidisciplinary approach. We report the successful anesthetic management and outcomes of five rare cases of adrenal tumors in adult and pediatric patients. Careful attention was paid to patient hydration, and salt supplementation was concurrently administered. Pharmacological therapy was started and required investigations, optimization was done preoperatively, and patients were admitted 2-3 days before surgery. During surgery, pheochromocytoma requires keen vigilance, invasive monitoring, appropriate anesthetic techniques, and vasodilator use during the perioperative period to tackle hypertensive crisis; vasopressors may be required postoperatively. All patients were clinically stable after surgery and were successfully discharged. [ABSTRACT FROM AUTHOR]