Pituitary Cell-Restricted T Box Factor, Tpit, Activates POMC Transcription in Cooperation with...
- Resource Type
- Article
- Authors
- Lamolet, Bruno; Pulichino, Anne-Marie; Lamonerie, Thomas; Gauthier, Yves; Blue, Thierry; Enjalbert, Alain; Drouin, Jacques
- Source
- Cell. 03/23/2001, Vol. 104 Issue 6, p849. 11p. 23 Color Photographs, 4 Black and White Photographs, 5 Diagrams, 4 Charts, 13 Graphs.
- Subject
- *PROOPIOMELANOCORTIN
*TRANSCRIPTION factors
*GENETICS
- Language
- ISSN
- 0092-8674
Investigates the transcriptional regulatory mechanisms of pro-opiomelanocortin (POMC) gene of pitiutary cell-restricted T box factor, Tpit. Cell-specific transcription of pituitary hormone-coding genes; Specificity of cooperation between Pitx homeoproteins and Tpit; Tpit gene mutations in patients with isolated pituitary POMC deficiency.