Tpit determines alternate fates during pituitary cell differentiation.
- Resource Type
- Article
- Authors
- Pulichino, Anne-Marie; Vallette-Kasic, Sophie; Peih-Ying Tsai, Judy; Couture, Catherine; Gauthier, Yves; Drouin, Jacques
- Source
- Genes & Development. 3/15/2003, Vol. 17 Issue 6, p738. 10p. 4 Color Photographs, 1 Diagram, 1 Graph.
- Subject
- *TRANSCRIPTION factors
*PROOPIOMELANOCORTIN
*PROTEINS
*GENE expression
*PITUITARY gland
- Language
- ISSN
- 0890-9369
Deals with a study which identified Tpit transcription factor as a cell-specific factor for expression of the pituitary proopiomelanocortin (POMC) gene. Role of POMC cell differentiation; Relationship of POMC-expressing lineages with pituitary cell types; Trans-repression of Tpit and SF1 activity.