Presumed antiphospholipid syndrome and thrombotic thrombocytopenic purpura: An infrequent association.
- Resource Type
- Article
- Authors
- Dolin, Hallie Hanna; Dziuba, Mark; Pappada, Scott M.; Papadimos, Thomas John
- Source
- Clinical Case Reports. Oct2019, Vol. 7 Issue 10, p1984-1988. 5p.
- Subject
- *THROMBOTIC thrombocytopenic purpura
*ANTIPHOSPHOLIPID syndrome
*PHOSPHOLIPID antibodies
*AUTOIMMUNE diseases
*VENOUS thrombosis
- Language
- ISSN
- 2050-0904
Antiphospholipid syndrome (APS) is an autoimmune disease that demonstrates antiphospholipid antibodies that cause hypercoagulability and leads to venous and arterial thrombosis. Autoantibodies to a disintegrin‐like and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS 13) play a role in the microthrombosis of thrombotic thrombocytopenic purpura in APS patients. [ABSTRACT FROM AUTHOR]