Rapid multiplex PCR panels for the management of ventilator-associated pneumonia: pondering strengths and weaknesses.
- Resource Type
- Article
- Authors
- Tomasello, Mara; Mangioni, Davide; Panigada, Mauro; Matinato, Caterina; Bandera, Alessandra
- Source
- Intensive Care Medicine. May2024, Vol. 50 Issue 5, p789-791. 3p.
- Subject
- *VENTILATOR-associated pneumonia
*NOSOCOMIAL infections
*GRAM-negative bacterial diseases
*COMMUNITY-acquired infections
*RESPIRATORY infections
- Language
- ISSN
- 0342-4642
This document is a comment on a review article about intensive care unit (ICU)-acquired infections in immunocompromised patients. The authors disagree with the review's view on the role of multiplex polymerase chain reaction (mPCR)-based tests in ventilator-associated lower respiratory tract infections (VA-LRTIs). They argue that mPCR tests are useful for ICU-acquired infections and can improve antibiotic stewardship in the ICU. The authors also discuss the strengths and limitations of mPCR-based tests based on their own study. They suggest that while waiting for further trials, physicians should be aware of the strengths and limitations of these tests. [Extracted from the article]