The emersion of the new coronavirus SARS COV 2 (Severe Acute Respiratory Syndrome Coronavirus 2) was rapidly characterized as a pandemic by WHO. The major manifestation of the virus is respiratory distress; however, the involvement of other organs should not be overlooked. The kidney is one of the most important target organs of the specific virus with acute kidney injury (AKI) described in 5-36% of COVID positive patients and an average 25% within the severely ill. Purp ose: The purpose of this study was to consider the incidence of AKI in patients with COVID 19 in our cohort and to better understand risk factors associated with AKI. Further, we wanted to investigate the impact of AKI on survival and in hospital mortality. Methods: Patients admitted to Evagelismos General Hospital with confirmed COVID-19 infection from 11th March until 22th May were investigated. Patients 18 years old as well as transplanted patients were excluded from this study. AKI was defined according to the AKI criteria. Results: From 99 patients with COVID-19 infection, AKI occurred in 41 (41.4%). A total of 44 patients (44.4%) were admitted to Intensive Care Unit (ICU) and 31 of them (70.5%) developed AKI. Of the 44 patients with AKI, 16 (39%) required renal replacement therapy. Hospital mortality, in total, was 16.2% (37% among patients with AKI versus 0.02% among those without AKI, p=0.000). Conclusion: AKI was common among patients hospitalized with COVID 19. AKI was associated with older age, clinical severity and existing CKD. [ABSTRACT FROM AUTHOR]