Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients.
- Resource Type
- Article
- Authors
- Ogata, Alana F; Cheng, Chi-An; Desjardins, Michaël; Senussi, Yasmeen; Sherman, Amy C; Powell, Megan; Novack, Lewis; Von, Salena; Li, Xiaofang; Baden, Lindsey R; Walt, David R
- Source
- Clinical Infectious Diseases. 2/15/2022, Vol. 74 Issue 4, p715-718. 4p.
- Subject
- *VIRAL antigens
*PROTEINS
*IMMUNOGLOBULINS
*COVID-19 vaccines
*BLOOD plasma
*IMMUNE system
*SEROLOGY
*MESSENGER RNA
*BIOLOGICAL assay
*WOMEN'S health services
*MEDICAL research
- Language
- ISSN
- 1058-4838
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA). [ABSTRACT FROM AUTHOR]