Narrowing the translational research gap by aligning replication concepts in basic and clinical neuroscience.
- Resource Type
- Article
- Authors
- Lewis, Alan S.; Nobis, William P.
- Source
- Journal of Neuroscience Methods. May2023, Vol. 392, pN.PAG-N.PAG. 1p.
- Subject
- *CLINICAL neurosciences
*EVIDENCE gaps
*TRANSLATIONAL research
*NERVOUS system
*PSYCHIATRIC treatment
- Language
- ISSN
- 0165-0270
Replicability and reproducibility are widely considered to be cornerstones of valid scientific research. Yet, the elements of replication in fundamental neuroscience studies do not fully overlap with the process of replication in clinical neuroscience involving patients. Here we discuss how better aligning the concept of replication across this translational spectrum might enhance the rate at which basic findings in the organization and function of the nervous system are leveraged to develop new treatments for psychiatric and neurological disorders. • The meaning of replicability and reproducibility is not standardized across fields. • The concept of replicability also differs between basic and clinical neuroscience. • Aligning basic and clinical neuroscience replicability might improve translation. [ABSTRACT FROM AUTHOR]