Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?
- Resource Type
- Case Study
- Authors
- PIVA, ISABELLA; MONTE, GIUSEPPE LO; GRAZIANO, ANGELA; MARCI, ROBERTO
- Source
- Journal of Clinical & Diagnostic Research. Nov2014, Vol. 8 Issue 11, p1-2. 2p.
- Subject
- *AUTOIMMUNITY
*SKIN diseases in pregnancy
*IMMUNE response
*HUMAN in vitro fertilization
*GESTATIONAL age
*ADRENOCORTICAL hormones
*OVUM donation
*PRURIGO
*DIAGNOSIS
- Language
- ISSN
- 0973-709X
Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period. [ABSTRACT FROM AUTHOR]