This article studies the patients with allergic rhinoconjunctivitis and asthma due to sensitization to Siberian hamster. The presence of exotic pets in dwellings is steadily increasing and new domestic allergens able to induce sensitization are appearing. Specific immunoglobulin E antibodies were determined against Siberian hamster hair (SH), common and golden hamsters. IgE immunoblotting with SH extract was performed. It is important to point out the lack of patient sensitization to common hamster allergens, which are usually tested when suspecting hamster allergy.