Intramolecular nucleophilic acyl substitution reactions of halo-substituted esters and lactones...
- Resource Type
- Article
- Authors
- Molander, Gary A.; McKie, Jeffrey A.
- Source
- Journal of Organic Chemistry. 12/3/93, Vol. 58 Issue 25, p7216. 12p. 6 Diagrams, 4 Charts.
- Subject
- *ESTERS
*LACTONES
*REACTIVITY (Chemistry)
- Language
- ISSN
- 0022-3263
Describes intramolecular nucleophilic acyl substitution reactions of halo-substituted esters and lactones. Applications of organosamarium reagents; Cyclization of halo-substituted esters; Preparation of stereodefined spirocyclic systems; Development of annulation methods; Superiority of samarium (II) iodide over other reducing agents.