C-reactive Protein Is a Strong Predictor of Mortality in Hemodialysis Patients.
- Resource Type
- Article
- Authors
- Rački, Sanjin; Zaputović, Luka; Mavrić, Žarko; Vujičić, Božidar; Dvornik, Štefica
- Source
- Renal Failure. 2006, Vol. 28 Issue 5, p427-433. 7p. 1 Diagram, 3 Charts, 3 Graphs.
- Subject
- *C-reactive protein
*CARDIAC patients
*CARDIOVASCULAR diseases
*HEMODIALYSIS patients
*CHRONIC kidney failure
- Language
- ISSN
- 0886-022X
Background . To establish the baseline cutoff value of C-reactive protein (CRP) that would predict increased overall and cardiovascular mortality in patients with end-stage renal disease (ESRD). Methods . A cohort of 270 prevalent hemodialysis patients treated at Rijeka University Hospital was eligible for the study. Monthly CRP measurements were performed for three consecutive months. Only the patients with CRP values varying 10.0 mg/L. The survival was evaluated by Kaplan-Meier curve. Results . During the two-year follow-up, 59 patients died. The major cause of death was cardiovascular disease (64%). Significantly higher overall and cardiovascular mortality was observed in group 3 when compared with groups 1 and 2 (χ 2 =11.97; P [ABSTRACT FROM AUTHOR]