Frontispiece: Organocatalytic Enantioselective Aza-Friedel-Crafts Reaction of Cyclic Ketimines with Pyrroles using Imidazolinephosphoric Acid Catalysts.
- Resource Type
- Article
- Authors
- Nakamura, Shuichi; Matsuda, Nazumi; Ohara, Mutsuyo
- Source
- Chemistry - A European Journal. 7/4/2016, Vol. 22 Issue 28, pn/a-N.PAG. 1p.
- Subject
- *AZOLES
*POLYMER aggregates
- Language
- ISSN
- 0947-6539
Chiral Phosphoric Acid Catalysts Organocatalytic enantioselective aza ‐ Friedel – Crafts reactions of cyclic ketimines with pyrroles or indole were catalyzed by imidazolinephosphoric acid catalysts. The reaction was applied to various 3H ‐ indol ‐ 3 ‐ ones to afford products in excellent yields and enantioselectivities. The graphics shows origami cranes that fly with expanded wings. The bis(imidazoline)/phosphoric acid catalysts also expand their wings like the origami cranes, and form a well ‐ fitting asymmetric space for substrate binding to let the reaction “fly”. The full story can be found in the Communication by S. Nakamura and colleagues on page 9478 ff. [ABSTRACT FROM AUTHOR]