One additional FD patient has been described with CRAO associated with marked optic disc edema [[14]]. Indeed, at the time of the diagnosis, our patient was screened for systemic involvement of FD, and only mild renal abnormalities were present. Graph: Supplementary file1 (DOCX 61 KB) References 1 Germain DP, Fouilhoux A, Decramer S. Consensus recommendations for diagnosis, management and treatment of Fabry disease in paediatric patients. Here we describe a FD female patient who presented with sequential and combined AION and CRAO in the same eye, and further conduct a literature review on CRAO and AION in FD. [Extracted from the article]