A variable universe fuzzy proportional‐integral‐differential (PID) algorithm was designed and first application for a laser power stabilization system. To validate the algorithm's effectiveness, it is applied to the simulation model of Simulink and the experimental system based on an acousto‐optic modulator. The results demonstrate that the variable universe fuzzy PID presents higher control precision, better robustness, and can suppress long‐term drift phenomena compared with the traditional feedback control algorithm. The algorithm design method in this paper has significant reference and guidance value for laser power stabilization system. [ABSTRACT FROM AUTHOR]