N-Heterocyclic carbene-catalyzed [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines.
- Resource Type
- Article
- Authors
- Gao, Zhong-Hua; Chen, Xiang-Yu; Cheng, Jin-Tang; Liao, Wei-Lin; Ye, Song
- Source
- Chemical Communications. 6/7/2015, Vol. 51 Issue 45, p9328-9331. 4p.
- Subject
- *HETEROCYCLIC compounds
*CARBENES
*SCHIFF bases
*IMINES
*ENANTIOSELECTIVE catalysis
- Language
- ISSN
- 1359-7345
An N-heterocyclic carbene-catalyzed enantioselective [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines was developed. The corresponding pyrazolidinones were obtained in good yields with moderate to good diastereoselectivities and excellent enantioselectivities. [ABSTRACT FROM AUTHOR]