To the Editor: Fungal infection in association with lung disease has emerged as a significant clinical problem.[1] Owing to a ubiquitous environmental abundance, fungal spores, inhaled daily, can reach even the smallest airways.[2] SP , sp [3] Although healthy individuals have effective immune mechanisms to clear this, individuals with anatomically abnormal airways and chronic respiratory disease (CRD) such as bronchiectasis are at higher risk of colonization and complications.[[2]] Use of high-throughput sequencing has allowed insight into the pulmonary microbiome. We have previously identified Candida, Penicillium, and Saccharomyces in healthy control subjects and in patients with bronchiectasis.[3] We showed that the bronchiectasis mycobiome is distinct and characterized by pathogenic fungal genera, including Aspergillus, Cryptococcus, and Clavispora. The fungal airway microbiome in cystic fibrosis and non-cystic fibrosis bronchiectasis [published online ahead of print June 13, 2020]. [Extracted from the article]