Metal-free and light-promoted radical iodotrifluoromethylation of alkenes with Togni reagent as the source of CF3 and iodine.
- Resource Type
- Article
- Authors
- Beniazza, Redouane; Douarre, Maxime; Lastécouères, Dominique; Vincent, Jean-Marc
- Source
- Chemical Communications. 3/28/2017, Vol. 53 Issue 25, p3547-3550. 4p.
- Subject
- *ALKENES
*ELECTROMAGNETIC waves
*IODINE
- Language
- ISSN
- 1359-7345
A light-promoted methodology for the iodotrifluoromethylation of alkenes was developed. For the first time a Togni reagent was exploited as the source of both the CF3 group and iodine atom. Preliminary mechanistic studies suggest that both CF3I and 2-iodobenzoic acid are direct sources of the iodine atom that is transferred to the products. [ABSTRACT FROM AUTHOR]