Effectiveness of mRNA COVID-19 Monovalent and Bivalent Vaccine Booster Doses Against Omicron Severe Outcomes Among Adults Aged ≥50 Years in Ontario, Canada: A Canadian Immunization Research Network Study.
- Resource Type
- Article
- Authors
- Grewal, Ramandip; Buchan, Sarah A; Nguyen, Lena; Nasreen, Sharifa; Austin, Peter C; Brown, Kevin A; Gubbay, Jonathan; Lee, Nelson; Schwartz, Kevin L; Tadrous, Mina; Wilson, Kumanan; Wilson, Sarah E; Kwong, Jeffrey C
- Source
- Journal of Infectious Diseases. 2/15/2024, Vol. 229 Issue 2, p394-397. 4p.
- Subject
- *BOOSTER vaccines
*SARS-CoV-2 Omicron variant
*IMMUNIZATION
*COVID-19
*MESSENGER RNA
- Language
- ISSN
- 0022-1899
We estimated the effectiveness of booster doses of monovalent and bivalent mRNA COVID-19 vaccines against Omicron-associated severe outcomes among adults aged ≥50 years in Ontario, Canada. Monovalent and bivalent mRNA COVID-19 booster doses provided similar strong initial protection against severe outcomes. Uncertainty remains around waning of protection from these vaccines. [ABSTRACT FROM AUTHOR]