Temporary Treatment during Primary HIV Infection Does Not Affect Virologic Response to Subsequent Long-Term Treatment.
- Resource Type
- Article
- Authors
- Grijsen, Marlous L.; Wit, Ferdinand W. N. M.; Jurriaans, Suzanne; Kroon, Frank P.; Schippers, Emile F.; Koopmans, Peter; Gras, Luuk; Lange, Joep M. A.; Prins, Jan M.
- Source
- PLoS ONE. Apr2014, Vol. 9 Issue 4, p1-5. 5p.
- Subject
- *HIV infections
*THERAPEUTICS
*VIROLOGY
*DRUG resistance
*GENETIC mutation
*COHORT analysis
*DATA analysis
- Language
- ISSN
- 1932-6203
Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI. [ABSTRACT FROM AUTHOR]