Low back pain (LBP) due to lumbar disk herniation could collaborate with various risk factors. In this study, we focused on analysis of lumbar disk herniation risk factors in patients with LBP. This comparative cross-sectional study was conducted in Hamedan-western Iran in 2014-2015. Overall, 58 cases with evidence of lumbar disk hernia were classified as a case group and 47 cases without evidence of lumbar disk herniation were classified as a control group. The data collection was performed by using a questionnaire and the statistical analysis was performed by using SPSS software. The analytic results indicated a meaningful correlation between demographic variables as body mass index (BMI) mean, occupation type and lumbar disk hernia (P<0.05). Furthermore, the abdominal circumference and the average heavy load carried by the participants throughout a day had a significant relationship with lumbar disk herniation (P<0.05). There are multiple risk factors for lumbar disk hernia regarding a combination of genetics and acquired characteristics and lifestyle. [ABSTRACT FROM AUTHOR]