Monkeypox is a virus that emerged in Africa in 1970 and is spread through contact with animals, people, and infected objects. It enters the body through ripped skin or the respiratory tract and can be transmitted from animals to humans through bites, scratches, or direct contact with body fluids or lesions. Human-to-human transmission occurs mainly through large respiratory droplets and can result in symptoms such as lethargy, fever, chills, body pains, lymphadenopathy, and rashes. Diagnosis can be confirmed through various tests, and treatment options include smallpox vaccines and antiviral drugs. The World Health Organization has declared monkeypox a global health emergency, with cases reported in several countries, including Pakistan. Pakistan, with its poor healthcare system, needs to be prepared for a potential monkeypox epidemic. The lack of healthcare infrastructure, training, and awareness in Pakistan increases the risk of undetected cases turning into large epidemics, so a concrete action plan is necessary. [Extracted from the article]