Job satisfaction of workers has captured the attention of social-researchers. Many organizations are facing reduced job satisfaction among employees. Little attention has been given to work-family conflict as one of the many causes for dissatisfaction of employees with their jobs. This research study has been conducted to examine the impact of three forms of work-to-family conflict (WFC): Time, Behavior and Strain-based, on job satisfaction of nurses in hospitals of district Bhakkar ,Pakistan. Data were collected via survey approach by distributing questionnaires among 120 nurses selected from the population of 350 via convenience sampling technique. Correlation and regression analysis showed that, in the direction of work-to-family conflict, WFC-Time and WFC-behavior were significant predictors of reduced job satisfaction. In the direction of family-to-work conflict, FWC-Behavior significantly predicted reduced job satisfaction. These findings have inferences and suggestions for nurses to manage their work and family commitments responsibly. [ABSTRACT FROM AUTHOR]