Spatial epigenome–transcriptome comapping technology.
- Resource Type
- Article
- Authors
- Jin, Ming-Zhu; Jin, Wei-Lin
- Source
- Trends in Cell Biology. Jun2023, Vol. 33 Issue 6, p449-450. 2p.
- Subject
- *GENETIC regulation
*EPIGENETICS
*GENE expression
*PHENOTYPES
- Language
- ISSN
- 0962-8924
Spatial omics facilitate an in-depth understanding of cell states and cell interactions. Recent work by Zhang et al. simultaneously seizes spatial epigenetic priming, differentiation, and gene regulation at nearly single-cell resolution by developing an epigenome–transcriptome comapping technology. This work displays how epigenetic features influence cell dynamics and transcriptional phenotypes at spatial and genome-wide levels. [ABSTRACT FROM AUTHOR]