Introduction Knee osteoarthritis affects over 48,6% of the population between 55 and 70 years old, being a degenerative type of affection which leads to invalidity and joint instability. The treatment of knee osteoarthritis is complex and it starts with medical treatment followed by the physicalkinetic treatment and it ends with the invasive joint infiltrations treatment. The therapeutical solution is enhanced by imagistic investigations but it is decided through mio-arthrokinetic clinical examination. Matherial and method The present paper presents 4 cases of knee osteoarthritis hospitalized at Techirghiol balneal and rehabilitation sanatorium throughout a period of 2 years, counting at least 3 successive hospitalizations which have benefited of complex recovery treatment and joint infiltrations. Results and discussions The evolution of the knee osteoarthritis cases under balneal, physical and kinetic treatment was constant and it lead towards progressive improvement. Conclusions Balneal treatment accompanied by joint infiltrations with hyaluronic acid and blood plateled enriched plasma represents the best choice for joint protection and to maintain joint mobility in normal limits. [ABSTRACT FROM AUTHOR]