Autophagy in cancer cytopathology: a case of intraoperative touch imprint of lung metastasis from TFE3-rearranged renal cell carcinoma.
- Resource Type
- Case Study
- Authors
- Gaggero, Gabriele; Ingaliso, Marta; Taietti, Davide
- Source
- Nowotwory. 2023, Vol. 73 Issue 2, p110-110. 1p.
- Subject
- *RENAL cell carcinoma
*AUTOPHAGY
*CELLULAR pathology
*METASTASIS
- Language
- ISSN
- 0029-540X
A case study of a 67-year-old man is presented who is diagnosed with a lung nodule suspected to be a metastasis from a rare type of renal cell carcinoma called translocation RCC (tRCC). Topics include the presence of intracytoplasmic hyaline globules (IHG) in the tumor; the autophagic nature of the globules; and the potential molecular relationship between autophagy and PD-L1 expression in cancer.