Measurement of single low-density lipoprotein particles by atomic force microscopy.
- Resource Type
- Article
- Authors
- Sakurai, Toshihiro; Takeda, Seiji; Takahashi, Jun-ya; Takahashi, Yuji; Wada, Norio; Trirongjitmoah, Suchin; Namita, Takeshi; Jin, Shigeki; Ikuta, Akiko; Furumaki, Hiroaki; Hui, Shu-Ping; Fuda, Hirotoshi; Fujikawa, Masato; Shimizu, Koichi; Chiba, Hitoshi
- Source
- Annals of Clinical Biochemistry. Nov2013, Vol. 50 Issue 6, p564-570. 7p.
- Subject
- *ATOMIC force microscopy
*LOW density lipoproteins
*HEART disease risk factors
*ULTRACENTRIFUGATION
*SCANNING probe microscopy
- Language
- ISSN
- 0004-5632
The article presents information on a study aimed at studying the feasibility of atomic force microscopy (AFM) for evaluation of the size of large low-density lipoprotein (LDL) as well as small dense LDL separated by ultracentrifugation. It is concluded that AFM can differentiate between sd-LDL and large LDL particles by their size and may be useful for evaluating risk for coronary artery disease (CAD).