Alarin but not its alternative-splicing form, GALP (Galanin-like peptide) has antimicrobial activity.
- Resource Type
- Article
- Authors
- Wada, Akihiro; Wong, Pooi-Fong; Hojo, Hironobu; Hasegawa, Makoto; Ichinose, Akitoyo; Llanes, Rafael; Kubo, Yoshinao; Senba, Masachika; Ichinose, Yoshio
- Source
- Biochemical & Biophysical Research Communications. May2013, Vol. 434 Issue 2, p223-227. 5p.
- Subject
- *ANTI-infective agents
*GALANIN
*PEPTIDES
*ESCHERICHIA coli growth
*STAPHYLOCOCCUS aureus
*BACTERIAL cell walls
*HEMOLYSIS & hemolysins
*ERYTHROCYTES
- Language
- ISSN
- 0006-291X
Highlights: • Alarin inhibits the growth of E. coli but not S. aureus. • Alarin’s potency is comparable to LL-37 in inhibiting the growth of E. coli. • Alarin can cause bacterial membrane blebbing. • Alalin does not induce hemolysis on erythrocytes. [ABSTRACT FROM AUTHOR]