This document discusses the use of a device that provides precise cooling of the skin during medical procedures. The device uses infrared sensors and CO2 cryogen to cool the skin to a specific temperature and duration. A study showed that using the device during injections for acne reduced pain and had no adverse effects. The device was also found to be effective for providing anesthesia during platelet-rich plasma (PRP) treatment for hair loss. The authors suggest that further research is needed to confirm the device's efficacy and explore other potential applications. Another section of the document discusses the use of hyaluronic acid injections for aesthetic sequelae after cleft lip surgery. The study evaluated the psychological impact, safety, and feasibility of the treatment, as well as ultrasound changes in the tissues. Seven patients were included in the study, and the results showed improvement in quality of life and scar appearance. [Extracted from the article]