Loss of PP4 contributes to diesel exhaust particles‐induced epithelial barrier integrity disruption and alarmins release.
- Resource Type
- Article
- Authors
- Yang, Feng‐Ming; Hu, Meng‐Chun; Weng, Chih‐Ming; Chuang, Hsiao‐Chi; Lan, Yu‐Ting; Su, Bing‐Hua; Heo, Kyung‐Sun; Kuo, Han‐Pin
- Source
- Allergy. Jun2023, Vol. 78 Issue 6, p1670-1673. 4p.
- Subject
- *CADHERINS
*METHACHOLINE chloride
*EPIDERMAL growth factor receptors
*POLLUTANTS
- Language
- ISSN
- 0105-4538
Bronchial specimens from patients with well-controlled asthma who had more intact airway epithelium were used for comparison with specimens from patients with severe asthma. Severe asthma: PP4 expression in the denuded epithelium of patients with severe asthma was very low. Loss of PP4 contributes to diesel exhaust particles-induced epithelial barrier integrity disruption and alarmins release. [Extracted from the article]