Subcutaneous ertapenem delivered by an Australian outpatient parenteral antimicrobial therapy service: a retrospective comparative efficacy study.
- Resource Type
- Article
- Authors
- Hiew, Jonathan; Whitmore, Timothy; McEvoy, Mahalia; Weatherall, Deborah; Ingram, Paul R.; Manning, Laurens
- Source
- Internal Medicine Journal. Oct2021, Vol. 51 Issue 10, p1717-1721. 5p.
- Subject
- *ERTAPENEM
*DRUG efficacy
*INTRAVENOUS therapy
*ANTI-infective agents
*RETROSPECTIVE studies
*PARENTERAL infusions
*COMPARATIVE studies
*TREATMENT effectiveness
*SUBCUTANEOUS injections
*OUTPATIENT services in hospitals
- Language
- ISSN
- 1444-0903
Subcutaneous (SC) administration of ertapenem in outpatient parenteral antimicrobial therapy (OPAT) services may be a practical alternative to intravenous delivery for complicated infections. The clinical features and outcomes according to route of administration were compared from a large Australian OPAT service. Chronic renal impairment was more common in the SC group, reflecting an opportunity for route of administration as a vein preservation strategy. Adverse events were uncommon and successful outcomes were not different between the groups. [ABSTRACT FROM AUTHOR]