Response to Selective RET Inhibition With LOXO-292 in a Patient With RET Fusion-Positive Lung Cancer With Leptomeningeal Metastases.
- Resource Type
- Case Study
- Authors
- Guo, Robin; Schreyer, Mark; Chang, Jason C.; Rothenberg, S. Michael; Henry, Dahlia; Cotzia, Paolo; Kris, Mark G.; Rekhtman, Natasha; Young, Robert J.; Hyman, David M.; Drilon, Alexander
- Source
- JCO Precision Oncology. 6/3/2019, Vol. 3, p1-6. 6p.
- Subject
- *MENINGEAL cancer
*METASTASIS
*LUNG cancer
- Language
- ISSN
- 2473-4284
The article presents a case study of a 33-year-old female never-smoker presented with cough and dyspnea. It notes the identification of the RET fusion-positive lung cancer with brain and leptomeningeal metastases; and mention the impactful intracranial response of patient to selective RET inhibition with LOXO-292.