Statin use and risk of nonmelanoma skin cancer: a nationwide study in Denmark.
- Resource Type
- Article
- Authors
- Arnspang, S; Pottegård, A; Friis, S; Clemmensen, O; Andersen, K E; Hallas, J; Gaist, D
- Source
- British Journal of Cancer. 1/6/2015, Vol. 112 Issue 1, p153-156. 4p. 1 Diagram, 1 Chart.
- Subject
- *SKIN cancer
*STATINS (Cardiovascular agents)
*SQUAMOUS cell carcinoma
*DANES
*BASAL cell carcinoma
*HEALTH
*CANCER risk factors
- Language
- ISSN
- 0007-0920
Background:Evidence is conflicting regarding statin use and risk of basal cell (BCC) and squamous cell skin cancer (SCC).Methods:Using Danish nationwide registries, we identified all patients with incident BCC/SCC during 2005-2009 and matched them to population controls. We computed odds ratios (ORs) for BCC and SCC associated with statin use.Results:We identified 38 484 cases of BCC and 3724 cases of SCC. Statin ever use was associated with ORs of 1.09 (CI: 1.06-1.13) for BCC and 1.01 (CI: 0.91-1.11) for SCC.Conclusions:Statin use was not associated with risk of SCC. Residual confounding plausibly explains the marginally increased risk of BCC. [ABSTRACT FROM AUTHOR]