Unmasking Coincident Hodgkin Lymphoma and Giant Cell Tumor: Insights from [18FF] FDG PET/CT.
- Resource Type
- Case Study
- Authors
- Al-Ibraheem, Akram; Moghrabi, Serin; Abdlkadir, Ahmed Saad; Haidar, Mohamad; Jaber, Omar
- Source
- Asia Oceania Journal of Nuclear Medicine & Biology. Jan2024, Vol. 12 Issue 1, p57-60. 4p.
- Subject
- *GIANT cell tumors
*HODGKIN'S disease
*KNEE joint
*HEMATOLOGIC malignancies
*COMPUTED tomography
- Language
- ISSN
- 2322-5718
Tenosynovial giant cell tumors represent a group of typically non-malignant tumors found within the joints and soft tissues. The occurrence of tenosynovial giant cell tumor alongside hematologic malignancies is an infrequent finding. Herein, we report a patient who presented with coinciding Hodgkin Lymphoma (HL) and tenosynovial giant cell tumor before chemotherapy initiation. The case was discovered during initial assessment using [18FF]fluorodeoxyglucose ([18FF]FDG) positron emission tomography/computed tomography (PET/CT) imaging for HL staging. An unrelated hypermetabolic mass within the left knee joint led to the discovery of this unusual case, which led to a CT-guided biopsy and tenosynovial giant cell tumor discovery. This was clearly demonstrated in interim and end-of-therapy PET/CT studies when all lymphomatous lesions had resolved but the tenosynovial giant cell tumor remained. This case serves as a reminder of the intricate nature of oncological pathology and emphasizes the need for thorough and vigilant diagnostic evaluation for optimal management plan. [ABSTRACT FROM AUTHOR]