Positive anti-MOG antibodies in a patient with Sjögren's syndrome and transverse myelitis.
- Resource Type
- Article
- Authors
- Jobling, Kerry; Ledingham, David; Wan-Fai Ng; Guadagno, Joe
- Source
- European Journal of Rheumatology. Apr2019, Vol. 6 Issue 2, p102-104. 3p.
- Subject
- *TRANSVERSE myelitis
*NEUROMYELITIS optica
*IMMUNOGLOBULINS
*NEUROLOGICAL disorders
*SYNDROMES
- Language
- ISSN
- 2148-4279
Twenty percent of patients with Sjögren's syndrome experience associated neurological disease. Transverse myelitis (TM) frequently forms part of a neuromyelitis optica spectrum disorder associated with the presence of anti-aquaporin 4 (AQP4) antibodies. We report the first described case of a patient who developed TM and the presence of a newly recognized antibody, anti-myelin oligodendrocyte protein (MOG), who went on to develop Sjögren's syndrome. AQP4 and MOG antibodies should be tested to guide prognostically the chances of further relapse as well as the type and duration of immunotherapy in patients with coexisting Sjögren's syndrome and TM. [ABSTRACT FROM AUTHOR]