The article discusses the challenges of diagnosing bipolar disorder in children and adolescents, which hinder research and clinical practice. The authors propose revising the current diagnostic taxonomy to focus on developmentally sensitive symptom clusters that reflect the evolution of the disorder over time. However, the article argues that a sole focus on symptoms may not improve diagnostic classification. Instead, the article suggests including more homogenous subtypes of bipolar disorder in a revised taxonomy, based on distinct clinical profiles that have been identified through research. The inclusion of these subtypes could advance risk prediction, pharmacotherapy, and discovery research. The article emphasizes the importance of a thorough clinical assessment, including a detailed family history, in making accurate diagnoses. [Extracted from the article]