Phosphatidylinositol Synthase and Diacylglycerol Platforms Bust a Move
- Resource Type
- Article
- Authors
- Bankaitis, Vytas A.; Grabon, Aby
- Source
- Developmental Cell. Nov2011, Vol. 21 Issue 5, p810-812. 3p.
- Subject
- *CYTOLOGY
*CELL membrane formation
*DIGLYCERIDES
*PHOSPHOINOSITIDES
*PROTEIN transport
*ENDOPLASMIC reticulum
- Language
- ISSN
- 1534-5807
challenge the dogma that phosphatidylinositol synthesis is restricted to the endoplasmic reticulum (ER) by showing that a mobile membrane compartment transports phosphatidylinositol synthase from the ER to numerous cellular compartments, including the plasma membrane. These findings significantly impact our view of phosphoinositide signaling in the cell. [ABSTRACT FROM AUTHOR]