Four! Drivers of melanoma differentiation—When to use iron.
- Resource Type
- Article
- Authors
- Fane, Mitchell E.; Sturm, Richard A.
- Source
- Pigment Cell & Melanoma Research. Nov2018, Vol. 31 Issue 6, p658-660. 3p.
- Subject
- *MELANOMA
*CELL populations
*CANCER cells
*CELL lines
*GENOMICS
- Language
- ISSN
- 1755-1471
The article discusses an article about a framework for the novel classification of a four-stepwise differentiation model within melanoma cell populations. An innovative approach and the use of prediction of subtype model from the Cancer Cell Line Encyclopedia (CCLE) and Genomics of Drug Sensitivity in Cancer (GDSC) datasets to explore matching drug sensitivity profiles is tackled. The authors also explore the refined framework of the multistage melanoma differentiation subtypes.