A study published in the journal Respirology suggests that long-term domiciliary oxygen therapy (LTDOT) may improve survival rates in patients with chronic obstructive pulmonary disease (COPD) who experience early desaturation during the six-minute walk test (6MWT). The study found that patients with early desaturation had worse survival rates compared to those without desaturation, but when prescribed LTDOT, their survival rates significantly improved. The study highlights the potential benefits of LTDOT in reducing intermittent hypoxemia and oxidative stress in patients with COPD. However, the study has limitations, such as a small sample size, and further research is needed to confirm these findings and explore other outcomes. [Extracted from the article]