([4]) followed a parallel group design in which the effect of 5 nights of sleep restriction (4 h of sleep per night), with or without daily high-intensity interval exercise (HIIE), were compared with a normal sleep (8 h) no exercise control group in healthy men. It was found that rates of MyoPS were significantly lower in participants undergoing 5 nights of sleep restriction compared to participants sleeping 8 h per night. Taken together, it is evident that sleep restriction alters one aspect of muscle protein turnover, MyoPS; however, the relative contribution of MPB, and associated signalling pathways to skeletal muscle homeostasis in this context is unclear. However, the lack of a positive control (i.e. normal sleep + HIIE) did not allow us to determine whether the exercise-induced stimulation of MyoPS following HIIE was attenuated by sleep restriction. [Extracted from the article]