Hypokalaemia-Induced Rhabdomyolysis after Treatment of Post-Kala-azar Dermal Leishmaniasis (PKDL) with High-Dose AmBisome in Bangladesh—A Case Report.
- Resource Type
- Article
- Authors
- Marking, Ulrika; den Boer, Margriet; Das, Asish Kumar; Ahmed, Elshafie Mohamed; Rollason, Victoria; Ahmed, Be-Nazir; Davidson, Robert N.; Ritmeijer, Koert
- Source
- PLoS Neglected Tropical Diseases. 6/12/2014, Vol. 8 Issue 6, p1-4. 4p.
- Subject
- *HYPOKALEMIA
*LEISHMANIASIS
*RHABDOMYOLYSIS
*PATIENT experience
*MYALGIA
*AMPHOTERICIN B
- Language
- ISSN
- 1935-2727
This article discusses a study conducted in Bangladesh on patients with post-kala-azar dermal leishmaniasis (PKDL) who were treated with high-dose liposomal amphotericin B (L-AMB). The study found that some patients experienced severe muscle pain and weakness, along with low potassium levels, after receiving L-AMB treatment. The researchers recommend further research to understand this adverse effect and emphasize the importance of strict safety monitoring when introducing a new drug in a different population. [Extracted from the article]