Progesterone receptor targeting with radiolabelled steroids: An approach in predicting breast cancer response to therapy.
- Resource Type
- Article
- Authors
- Cunha, Susana; Gano, Lurdes; Ribeiro Morais, Goreti; Thiemann, Thies; Oliveira, Maria Cristina
- Source
- Journal of Steroid Biochemistry & Molecular Biology. Sep2013, Vol. 137, p223-241. 19p.
- Subject
- *PROGESTERONE receptors
*GENE targeting
*RADIOLABELING
*STEROIDS
*BREAST cancer treatment
*POSITRON emission tomography
*RADIOLIGAND assay
- Language
- ISSN
- 0960-0760
Highlights: [•] Progesterone receptor status is a good predictor of tumour responsiveness to therapy. [•] PET/SPECT are imaging techniques that allow analysis of biological processes at molecular and metabolic levels. [•] Most relevant PET/SPECT progesterone radioligands for breast cancer imaging are discussed. [Copyright &y& Elsevier]