A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration.
- Resource Type
- Article
- Authors
- Xinhui Wu; Bos, I. Sophie T.; Conlon, Thomas M.; Ansari, Meshal; Verschut, Vicky; van der Koog, Luke; Verkleij, Lars A.; D'Ambrosi, Angela; Matveyenko, Aleksey; Schiller, Herbert B.; Königshoff, Melanie; Schmidt, Martina; Kistemaker, Loes E. M.; Yildirim, Ali Önder; Gosens, Reinoud
- Source
- Science Advances. 3/25/2022, Vol. 8 Issue 12, p1-14. 14p.
- Subject
- *CLOCK genes
*LUNGS
*DRUG target
*PROSTAGLANDIN receptors
*REGENERATION (Biology)
*LIGANDS (Chemistry)
- Language
- ISSN
- 2375-2548
The article presents a study which explores transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration. It mentions that findings conclude that specific targeting of EP and IP receptors offers therapeutic potential for injury to repair in chronic obstructive pulmonary disease.