Introduction. Toxoplasmosis is an infection caused by the Toxoplasma gondii protozoan, cats being the permanent hosts. The prevalence of the parasite depends on the geographic area and its genotype. More care should be provided to the pregnant woman, who must be informed, diagnosed and treated in time. The majority of infections concerning the mother do not affect the pregnancy, they are subclinic. For the immunocompetent people, the initial infection provides immunity and the infection before pregnancy eliminates any risk of vertical transmission. The maternal infection presents itself with a four times higher risk of prematurity. The incidence and the severity of the maternal toxoplasmosis depend on the moment of infection and the gestational age. The risk of fetal infection increases with the duration of pregnancy. Methodology. The study was performed over a period of five years (2015-2019), at the “Elena Doamna” Clinical Hospital of Obstetrics and Gynecology, Iaşi, to provide a better view on the incidence and influence of toxoplasmosis in pregnant women. Most cases of toxoplasmosis were concentrated in rural areas, in the group age of 20-29 years old (41 cases; 67%), in women with more than one pregnancy (66 cases; 84%), in total 87 cases (2%) from 5250 pregnancies and births from the obstetric department and 15 cases (17%) from the neonatology department. Conclusions. The general practitioner, who needs to report all toxoplasmosis cases in pregnant women and colaborate with the obstetrician, plays a very important role. The detection is made through serological tests (TORCH profile), after which we choose an individualised treatment for each pregnant woman. [ABSTRACT FROM AUTHOR]