Tumor organoid-originated biomarkers predict immune response to PD-1 blockade.
- Resource Type
- Article
- Authors
- Cimen Bozkus, Cansu; Bhardwaj, Nina
- Source
- Cancer Cell. Sep2021, Vol. 39 Issue 9, p1187-1189. 3p.
- Subject
- *TUMOR markers
*IMMUNE response
- Language
- ISSN
- 1535-6108
Despite the demonstrated efficacy and broad applicability of checkpoint blockade, the mechanisms by which it exerts its antitumor effects are incompletely understood. A recent article in Nature Medicine describes an ex vivo platform for assessing early responses to checkpoint blockade and the properties of tumor immune contexture in correlation to clinical responses. [ABSTRACT FROM AUTHOR]