The effect of a newly developed mini-light-emitting diode catheter for interstitial photodynamic therapy in pancreatic cancer xenografts.
- Resource Type
- letter
- Authors
- Kim, So-Young; Cho, Eun A.; Bae, Sang Mun; Kim, Sang-Yeob; Park, Do Hyun
- Source
- Journal of Translational Medicine. 6/7/2021, Vol. 19 Issue 1, p1-4. 4p.
- Subject
- *PANCREATIC cancer
*PHOTODYNAMIC therapy
*LIGHT emitting diodes
*CANCER treatment
*CATHETERS
*XENOGRAFTS
*MICROBIAL fuel cells
- Language
- ISSN
- 1479-5876
In this preliminary report, 3 mini-LED chips (2 with side and 1 with forward firing) a with 2.5-mm diameter and 5-mm diffuser length catheter were used for administering PDT in pancreatic cancer xenografts (Fig. 2 In vivo efficacy of interstitial-photodynamic therapy (i-PDT) in BxPC3 tumor-bearing mice within 15 days in different groups treated with Photofrin (Phf) and chlorin e6 (Ce6). Both LED-based i-PDT (100 J/cm2) with Photofrin and Ce6 had better suppression of tumor growth than in other groups. [Extracted from the article]