Human autoantibodies specific for the alpha1A calcium channel subunit reduce both P-type and Q-...
- Resource Type
- Article
- Authors
- Pinto, Ashwin; Gillard, Samantha; Moss, Fraser; Whyte, Kathryn; Brust, Paul; Williams, Mark; Stauderman, Ken; Harpold, Michael; Lang, Bethan; Newson-Davis, John; Bleakman, David; Lodge, David; Boot, John
- Source
- Proceedings of the National Academy of Sciences of the United States of America. 07/07/98, Vol. 95 Issue 14, p8328. 6p. 13 Graphs.
- Subject
- *MYASTHENIA gravis
*AUTOANTIBODIES
- Language
- ISSN
- 0027-8424
Examines the specificity of Lambert-Eaton myasthenic syndrome (LEMS) IgGs for cloned human neuronal voltage-dependent calcium channel (VDCC). Role of VDCC in neurotransmitter release at the synpase; Classification of VDCC into various subtypes; What is LEMS.