Cognitive Strategy-Specific Increases in Phosphorylated cAMP Response Element-Binding Protein and c-Fos in the Hippocampus and Dorsal Striatum.
- Resource Type
- Article
- Authors
- Colombo, Paul J.; Brightwell, Jennifer J.; Countryman, Renee A.
- Source
- Journal of Neuroscience. 4/15/2003, Vol. 23 Issue 8, p3547. 8p. 5 Diagrams, 3 Graphs.
- Subject
- *HIPPOCAMPUS (Brain)
*MEMORY
*PHOSPHORYLATION
*CYCLIC adenylic acid
*LEARNING
*PROTEINS
*ADENOSINE monophosphate
- Language
- ISSN
- 0270-6474
Presents information on a study which investigated the dissociable role of hippocampus and striatum in memory and their importance to 'place' and 'response' learning, using rats trained on a cross maze task. Relation of the formation of memory for a place strategy to sustained phosphorylation of cyclic adenylic acid (cAMP) response element-binding (CREB) protein; Regional activity of CREB; Results and discussion.